Ipamorelin
Selective growth hormone secretagogue / ghrelin-receptor (GHSR-1a) agonist (investigational) · Pre-filled pen
Ipamorelin is studied as a selective growth-hormone secretagogue that acts on the ghrelin / growth-hormone-secretagogue receptor (GHSR-1a) to prompt the pituitary to release the body's own growth hormone in a pulsatile pattern. Research emphasises a comparatively selective profile, with limited activation of prolactin- and cortisol-linked pathways relative to broader secretagogues. Long-term human outcome data remain limited.
Studied use areas
- Research into stimulation of the body's own GH release
- Recovery and tissue-regeneration research
- Body-composition and lean-mass research
- Sleep-related recovery research
Safety & status
- Educational information only — not medical advice; use requires physician supervision
- Investigational and not an approved therapy for these uses
- Prohibited in competitive sport: listed under WADA Prohibited List class S2 (peptide hormones, growth factors, related substances and mimetics — growth hormone secretagogues, where ipamorelin is named)
- Stimulating the GH axis can affect glucose metabolism and fluid balance, so suitability and monitoring must be assessed by a physician
⚕ Clinical note: This card is educational and is not medical advice, a protocol or a promise of results. Ipamorelin is investigational; any use must be individualised and supervised by a qualified physician.
Evidence: Investigational (Grade C) — limited human data, not an approved therapy · References: Raun et al., European Journal of Endocrinology 1998; Gobburu et al., Pharmaceutical Research 1999; Beck et al., International Journal of Colorectal Disease 2014; Sigalos & Pastuszak, Sexual Medicine Reviews 2018



